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姓名：文烈伟 职称：副研究员/助理教授 导师类型：硕导 团队名称：高分子与纳米复合材料 邮箱：wenliewei@bit.edu.cn |
研究领域
主要研究领域为：
- 光/微波敏感型生物医用纳米材料
- 天然活性成分衍生型纳米药物
- 纳米生物材料的抗肿瘤/抗菌效应机制
教育经历
2012年9月–2018年6月：华南师范大学 生物物理学专业 博士学位
2007年9月–2012年6月：成都中医药大学 生物科学专业 学士学位
工作经历
2024年12月–今：北京理工大学（珠海）副研究员/助理教授
2023年8月–2024年12月：珠海市人民医院（暨南大学珠海临床医学院） 副研究员
2023年1月–2023年7月：澳门大学 中华医药研究院 博士后
2018年7月–2022年12月：珠海市人民医院（暨南大学附属珠海医院） 助理研究员
学术成果（第一或通讯作者）
1.Yu Wang, Famin Huang, Yichao Fu, Shuangfeng Tang, Liewei Wen*, Huan Qin*, Electric vector-adapted thermoacoustic computed tomography for dynamic imaging sub-organ features in deep tissue. Applied Physics Letters, 2025, doi: 10.1063/5.0275324
2.Yitian Zhang#, Bitao Li#, Jiawen He, Ya Meng, Meixiao Zhan, Cuixia Lu, Yong Li*, Feiyu Niu*, Liewei Wen*, Hemoglobin-loaded hollow mesoporous carbon-gold nanocomposites enhance microwave ablation through hypoxia relief. Journal of Nanobiotechnology, 2025, 23 (1), 326
3.Ruie Chen#, Liewei Wen#,*, Feng Guo, Jiawen He, Ka Hong Wong, Meiwan Chen*, Glutathione-scavenging natural-derived ferroptotic nano-amplifiers strengthen tumor therapy through aggravating iron overload and lipid peroxidation. Journal of Controlled Release, 2025, 379, 866-878
4.Tao Zhong#, Ning Liu#, Juan Wang, Songbo Xie, Lisheng Liu, Minglei Wang, Fei Wu, Xiaozheng Chen, Changyan Xiao, Xiaoxiao Gongye, Meng Wu, Liewei Wen*, Jinming Yu*, Dawei Chen*. ASPM induces radiotherapy resistance by disrupting microtubule stability leading to chromosome malsegregation in non-small cell lung cancer, Exploration, 2025, e20230024
5.Fengfeng Xiao#, Yongkang Liu#, Yanhong Su, Xu He, Ligong Lu, Meixiao Zhan, Liewei Wen*, Yunlu Dai*, Bing Liu*, Biodegradable Poly (amino acid)-Bismuth Nanotheranostic Agents for CT/MR Imaging and Photothermal-Chemodynamic Synergistic Therapy. Chem & Bio Engineering, 2024, 1 (5), 448-460
6.Yunong Ma#, Xi Zhao#, Peilin Tian, Kexin Xu, Jiayang Luo, Honghui Li, Mingqing Yuan, Xu Liu, Yanping Zhong, Pingzhen Wei, Jiaxing Song*, Liewei Wen*, Cuixia Lu*, Laser-ignited lipid peroxidation nanoamplifiers for strengthening tumor photodynamic therapy through aggravating ferroptotic propagation and sustainable high immunogenicity, Small, 2024, 20: 2306402
7.Jiawen He#, Xumei Ouyang#, Fengfeng Xiao, Ning Liu*, Liewei Wen*. Imaging-Guided Photoacoustic-Immunotherapy Based on the Polydopamine Functionalized Black Phosphorus Nanocomposites, ACS Applied Materials & Interfaces, 2023, 15(47): 54322-54334.
8.Liewei Wen#,*, Hongyi Liu#, Cong Hu#, Zixuan Wei, Ya Meng, Cuixia Lu, Yanhong Su, Ligong Lu, Hui Liang*, Qingbo Xu*, Meixiao Zhan*, Thermoacoustic imaging-guided thermo-chemotherapy for hepatocellular carcinoma sensitized by a microwave-responsive nitric oxide nanogenerator, ACS Applied Materials & Interfaces, 2023, 15(8): 10477-10491.
9.Jiawen He#, Ruixiang Song#, Fengfeng Xiao, Meng Wang*, Liewei Wen*, Cu3P/1-MT Nanocomposites Potentiated Photothermal-Immunotherapy. International Journal of Nanomedicine, 2023: 3021-3033.
10.Zixuan Wei#, Xiaoya Yu#, Mao Huang, Liewei Wen*, Cuixia Lu*, Nanoplatforms Potentiated Ablation-Immune Synergistic Therapy through Improving Local Control and Suppressing Recurrent Metastasis, Pharmaceutics, 2023, 15(5): 1456.
11.Yunong Ma#, Fengfeng Xiao#, Cuixia Lu*, Liewei Wen*. Multifunctional Nanosystems Powered Photodynamic Immunotherapy. Frontiers in Pharmacology, 2022, 13: 905078.
12.Honghui Li#, Mao Huang#, Zixuan Wei, Jiawen He, Yunong Ma, Cuixia Lu, Albert Jin*, Zhixiong Wang*, Liewei Wen*. Hydrogen sulfide activatable metal-organic frameworks for Fluorescence Imaging-Guided Photodynamic Therapy of colorectal cancer, Frontiers in Bioengineering and Biotechnology, 2022, 10: 1032571.
13.Honghui Li#, Ying Zhang#, Lingxia Liang#, Jiaxing Song, Zixuan Wei, Shuyue Yang, Yunong Ma, Wei R Chen, Cuixia Lu*, Liewei Wen*, Doxorubicin-Loaded Metal-Organic Framework Nanoparticles as Acid-Activatable Hydroxyl Radical Nanogenerators for Enhanced Chemo/Chemodynamic Synergistic Therapy. Materials, 2022, 15 (3), 1096.
14.Wenjun Ni, Yongxiang Li, Lingxia Liang, Shuyue Yang, Meixiao Zhan, Cuixia Lu *, Ligong Lu*, Liewei Wen*, Tumor microenvironment-responsive nanodrug for clear-cell renal cell carcinoma therapy via triggering waterfall-like cascade ferroptosis. Journal of Biomedical Nanotechnology, 2022, 18(2): 327-342.
15.Lingxia Liang#, Liewei Wen#,*, Yuqing Weng#, Jiaxing Song, Honghui Li, Ying Zhang, Xu He, Wei Zhao, Meixiao Zhan, Yong Li, Ligong Lu, Yongjie Xin*, Cuixia Lu*, Homologous-targeted and tumor microenvironment-activated hydroxyl radical nanogenerator for enhanced chemoimmunotherapy of non-small cell lung cancer. Chemical Engineering Journal, 2021, 425, 131451.
16.Yihao Duan, Zhongwen Cheng, Tengsen Qiu, Liewei Wen*, Kedi Xiong*. Spherical-matching hyperbolic-array photoacoustic computed tomography. Journal of Biophotonics, 2021, 14 (6), e202100023.
17.Yujing Li, Fei Ye, Shanxiang Zhang, Wenjun Ni, Liewei Wen*, Huan Qin*, Carbon-coated magnetic nanoparticle dedicated to MRI/photoacoustic Imaging of tumor in living mice. Frontiers in Bioengineering and Biotechnology, 2021, 9: 800744.
18.Liewei Wen, Sihua Yang, Junping Zhong, Quan Zhou, Da Xing. Thermoacoustic Imaging and Therapy Guidance based on Ultra-short Pulsed Microwave Pumped Thermoelastic Effect Induced with Superparamagnetic Iron Oxide Nanoparticles. Theranostics, 2017, 7 (7), 1976-1989.
19.Liewei Wen, Wenzheng Ding, Sihua Yang, Da Xing. Microwave pumped high-efficient thermoacoustic tumor therapy with single wall carbon nanotubes. Biomaterials, 2016, 75, 163-173.
20.Liewei Wen, Sihua Yang, Da Xing. Ultra-short microwave pulse induced thermoacoustic therapy for deep-seated tumor with mitochondria-targeting single wall carbon nanotubes. 2016 Asia Communications and Photonics Conference (ACP), 1-3
21.Junping Zhong#, Liewei Wen#, Sihua Yang, Liangzhong Xiang, Qun Chen, Da Xing. Imaging-guided high-efficient photoacoustic tumor therapy with targeting gold nanorods. Nanomedicine: Nanotechnology, Biology, and Medicine, 2015, 11, 1499-1509.
荣誉奖励
1.国家奖学金，2012
2.华南师范大学研究生“十佳学术论文”奖，2016
3.博士研究生国家奖学金，2017
3.华南师范大学研究生“十佳学术论文”奖，2018
4.Exploration 编委贡献个人奖，2023
5.Journal of Nanobiotechnology, Outstanding Reviewer Awards, 2024
社会兼职
1.2023年-至今 Exploration, 学术编辑
2.2023年-至今 广 东省生物物理学会理事
3.2024年-至今 Nano TransMed, 青年编委
4.2024年-至今 Interdisciplinary MEDICINE, 青年编委
5.2024年 Frontiers in Chemistry, 客座编辑
6.2025-至今 Oncology and Translational Medicine, 青年编委
7.2025-至今 中国老年保健医学研究会老年健康科技创新分会委员