姓名：许杰华 职称：主任医师 副教授 导师类型：博导 团队名称：附属医院 邮箱：xujhgz3@163.com

研究领域

研究方向：中药学、药学、核药、核素掺杂量子点；肿瘤（特别是肝癌）核素诊疗探针研究；影像组学。

教育经历

1994.9-1999.6 中山医科大学（现中山大学） 医学影像学本科/学士

1999.9-2002.6 中山大学影像医学与核医学 硕士生

2006.9-2009.6 中山大学影像医学与核医学博士生

2013.3-2014.3 美国University of Florida 访问学者

工作经历

2020.10- 至今 珠海市人民医院（北京理工大学附属医院）核医学科 主任

2017.12-2020.10 中山大学附属第三医院 核医学科 主任医师、副教授

2012.12-2020.10中山大学附属第三医院 核医学科 副主任医师、副教授

2010.12-2017.12中山大学附属第三医院 核医学科 副主任医师

2004.12-2010.12中山大学附属第三医院 核医学科 主治医师

2002.07-2004.12中山大学附属第三医院 核医学科 住院医师

学术成果

1）Zhao Li, Jiefei Sui, Qiong Jin, Aili Ma, Shisong Han, Xiaoling Zhang,* Jiehua Xu* and Jiatao Zhang*，Research progress on radioactive quantum dots for biomedical applications，Nano Research NARE-D-25-03433（Nov. 4, 2025 :under revision

2) jiangkun Yu，Xue Lin, Wenshan Huang, Shisong Han，Jie Qin,* Jie-Hua Xua,*Target Identification of the Hepatocellular Carcinoma-Specific Aptamer JHIT2e and Construction of Engineered Nanotrains for Synergistic Chemo-radiotherapy Molecular Pharmaceutics :under revision

3) Nie DA, Yu J, Huang W, Li GH, He XY, Xu JH. The role of microglia in neurodegenerative diseases. Mol Immunol. 2025 Sep;185:127-135. doi: 10.1016/j.molimm.2025.07.014. Epub 2025 Jul 31. PMID: 40749622.

4）Qian Shang; Shen-Huan Li; Yu-Ting He; Yun Zhang; Ting Fu; Shi-Song Han; Wen-Shan Huang; Xue-Qiang Wang*; Jie-Hua Xu*, High contrast bioimaging of tumor and inflammation with a bicyclic dioxetane chemiluminescent probe, Analytical Chemistry.2024,96(6):2286-2291. (2023 IF:7.4)

5)Wen-Shan Huang; Yang-Lin He; Jie Liang; Yu-Lin Su; Jie-Hua Xu*, Jejunal cavernous hemangioma mimicking malignancy with increased activity on 18 F-FDG PET/CT, Clinical Nuclear Medicine,48 (5) :409-410. (2023 IF:10.6)

6)Jie Liang; Wen-Shan Huang; Wen-Zhen Lan; Yong Li*; Jie-Hua Xu*, 18 F-FDG PET/CT of a rare sternal osteoblastoma in a man with history of lymphoma, Clinical Nuclear Medicine, 2023, 48 (4): 324-326. (2023 IF:10.6)

7)Gui-Xiong Zhang#; Yan-Lan Liu#; Min Yang; Wen-Shan Huang; Jie-Hua Xu*, An aptamer-based, fluorescent and radionuclide dual-modality probe, BIOCHIMIE, 2020, V171~172, 55-62. (2023 IF:4.372,被引用次数：19) .

8)Wen-Shan Huang#; Yongjiang Zheng#; Jia-Wen Chen#; Gui-Xiong Zhang; Jie-Hua Xu*, FDG PET/CT imaging of pancreatic plasmacytoma, Clinical Nuclear Medicine,2020, 45 (6) ：489-491. (2023 IF：10.6)

9)JieHua Xu#; I-Ting Teng#; Liqin Zhang; Stefanie Delgado; Carole Champanhac; Sena Cansiz; Cuichen Wu; Hong Shan; Weihong Tan*, Molecular recognition of human liver cancer cells using DNA aptamers generated via Cell-SELEX, PLos One, 2015, 10 (5) : e0125863. (2023 IF：3.752，被引57次)

10)Gui-Xiong Zhang#;Yongjiang Zheng#;Wen-Shan Huang#;Min Yang;Jie-Hua Xu*, FDG PET/CT findings of unsuspected pulmonary epithelioid angiosarcoma manifested as a brain metastasis, Clinical Nuclear Medicine, 2019, 44 (8) , e489-e491. (2023 IF:10.6)

11)杨敏；黄文山；查悦明；张桂雄；许杰华*，131I标记的肝癌核酸适配子在荷瘤小鼠体内生物分布及显像，中华肝脏外科手术学电子杂志, 2019, 8（3）：260-264。

12)许杰华#*；张桂雄；杨敏；黄文山，131I标记适配子的优化研究及其稳定性的评价，新医学， 2019，50（12）：894-897。

13)Gui-Xiong Zhang#;Ting Jiang#;Yong-Jiang Mao#; Min Yang;Jie-Hua Xu*, Cerebral abscesses and osteomyelitis caused by fish bone impaction on FDG PET/CT imaging, Clinical Nuclear Medicine, 2018,43 (3) : 209-212. (2023 IF:10.6)

14)周子东；查悦明；黄文山；杨敏；张桂雄；许杰华*，18F-FDG PET-CT影像组学鉴别中低分化肝细胞癌和肝内胆管细胞癌，中华肝脏外科手术学电子杂志，2019，8（02）：154-158。（被引用次数：21）

15)Jie-Hua Xu#*;Pei-Qiang Cai#;Zi-Dong Zhou;Jie Qin;Xiao-Ping Lin, A rare case of a postoperative submandibular exophytic goiter in a patient with a recurrent normotopic nodular goiter, Clinical Nuclear Medicine, 2016,41 (6) : 485-487. (2023 IF:10.6)

16)Jie-Hua Xu;Yu-Xiong Su;Mu-Hua Cheng;Yong Zhang;Ping Wang;Ju Jiao;Chun-Xing Wu;Gui-Qing Liao;Hong Shan*, Using Tc-99m pertechnetate scintigraphy to predict the outcome of sialoendoscopy in obstructive submaxillaritis, Clinical Nuclear Medicine, 2010,35 (2): 77-79. (2023 IF:10.6)

17)T Jiang#;J H Xu#*;Y Zou;R Chen;L R Peng;Z D Zhou;M Yang, Diffusion-weighted imaging (DWI) of hepatocellular carcinomas: a retrospective analysis of the correlation between qualitative and quantitative DWI and tumour grade, Clinical Radiology, 2017,72 (6) : 465-472. (被引31次)

18)Rui Chen#*;Jiehua Xu#;Yanling She;Ting Jiang;Shanyao Zhou;Huacai Shi;Cheng Li,Necrostatin-1 protects C2C12 myotubes from CoCl2-induced hypoxia, International Journal of Molecular Medicine, 2018,41 (5) : 2565-2572. (2023 IF：5.314,被引39次)

19)Yongjiang Zheng#*;Jie-hua Xu#;Shengran Liang#;Dongjun Lin and Santasree Banerjee*, Whole exome sequencing identified a novel heterozygous mutation in HMBS gene in a Chinese patient with acute intermittent porphyria with rare type of mild anemia, Fronties in Genetics, 2018, 9: 129. (被引用次数：37)

20)Jiehua Xu#*; Jie Qin#; Wei-zhen Chen; Ju Jiao; Ping Wang; Jian-fang Li; Yong Zhang; Mu-hua Cheng, 99mTc MAA pulmonary perfusion scintigraphy in 2 cases of anomalous systemic arterial supply to normal basal segments of the left lower lobe of the lung, Clinical Nuclear Medicine, 2012，37(4):377-379. (2023 IF: 10.6，被引：6次).

21)Pei-qiang Cai#; Yao-pan Wu#; Li Li; Rong Zhang; Chuan-miao Xie; Pei-hong Wu* Jie-hua Xu*, CT and MRI of radiation-induced sarcomas of the head and neck following radiotherapy for nasopharyngeal carcinoma,Clinical Radiology, 2013, 68(7):683-689. (2023 IF: 2.6，被引：26次)

22)许杰华；易慧敏；程木华；吴春兴；焦举；邱小英；江婷；单鸿*，99Tcm-聚合白蛋白显像在肝肺综合征及肝移植中的应用，中华核医学与分子影像杂志, 2009，29（4）:259-262。

22)许杰华；李丹；于春鹏；周斌；颜荣华；王劲；朱康顺；单鸿*，SPIO标记下大鼠骨髓间充质干细胞生物学特性及多向分化潜能及体外MR成像，中山大学学报（医学科学版），2009, 30（02）:142-147。